Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors PDF Scaricare GRATUITO [Mobi . ePub]

vane sir john r. (curatore); botting jack h. (curatore); botting r.m. (curatore) - improved non-steroid anti-inflammatory drugs: cox-2 enzyme inhibitors

vane sir john r. (curatore)

Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors

lingue: Italiano
Prezzo: GRATUITO

>> Scarica il libro <<

Informations:
Formato libro:pdf.epub.lit.ibooks.mobi.mp3
rb.lrf.ogg.txt.rtf.doc

Dettagli

Genere:Libro
Lingua: Inglese
Editore:

Springer

Pubblicazione: 12/2011
Edizione: Softcover reprint of the original 1st ed. 1996

ISBN:

9789401090315

Condizione: Nuovo
Dimensioni: 235 x 155 mm Ø 405 gr
Formato: Brossura
Pagine Arabe: 200

In 1971, Vane proposed that the mechanism of action of the aspirin-like drugs was through their inhibition of prostaglandin biosynthesis. Since then, there has been intense interest in the interaction between this diverse group of inhibitors and the enzyme known as cyclooxygenase (COX). It exists in two isoforms, COX-l and COX-2 (discovered some 5 years ago). Over the last two decades several new drugs have reached the market based on COX-l enzyme screens. Elucidation of the three-dimensional structure of COX-l has provided a new understanding for the actions of COX inhibitors. The constitutive isoform of COX, COX-l has clear physiological functions. Its activation leads, for instance, to the production of prostacyclin which when released by the endothelium is anti-thrombogenic and anti-atherosclerotic, and in the gastric mucosa is cyto­ protective. COX-l also generates prostaglandins in the kidney, where they help to maintain blood flow and promote natriuresis. The inducible isoform, COX-2, was discovered through its activity being increased in a number of cells by pro­ inflammatory stimuli. A year or so later, COX-2 was identified as a distinct isoform encoded by a different gene from COX-I. COX-2 is induced by inflammatory stimuli and by cytokines in migratory and other cells. Thus the anti-inflammatory actions of non-steroid anti-inflammatory drugs (NSAIDs) may be due to the inhibition of COX-2, whereas the unwanted side-effects such as irritation of the stomach lining and toxic effects on the kidney are due to inhibition of the constitutive enzyme, COX-I.

Leggi online:777
Scarica libri:665

Listino prezzi per i libri:

Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors.un libro {un e-libro} – EUR(0.00€)

Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors.audiolibro – EUR(0.00€)

Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors.PDF

Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors.EPUB

Aggiungi molta esperienza e conoscenza. Qui puoi ottenere lo speciale faggio ePub PDF Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors per te. Su questo sito ci sono libri in PDF, Kindle, Ebook, ePub e Mobi. Naturalmente, questo libro di Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors PDF Download è molto interessante da leggere. Non devi comprare perché ti offriamo gratuitamente scaricando qui. Prendi questo Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors PDF Kindle Prenota ora!

Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors.pdf

Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors.epub

TAGS:

Scarica online Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors MOBI TXT;

Scarica Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors pdf AWZ online;

Gratuitamente Scarica Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors PDF TXT;

Scarica Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors DOC epub torrent;

leggere PDF Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors pDF Kindle;

libro Scarica Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors Ibook pdf Italiano;

Gratuitamente Scaricare Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors Kindle Ibook epub;

Gratuitamente Scaricare PDF Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors Txt Doc torrent;

PDF Scaricare Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors dvd kindle;

Scaricare Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors FB2 mp3 online;

leggere online Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors txt EPUB torrent;

Gratis Scaricare Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors PDF txt online;

PDF Scaricare Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors FB2 EPUB;

libro Scaricare Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors txt doc;

Gratis
libro Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors PDF e-libro;

Scaricare Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors TXT libro;

Pdf elibro torrent Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors libri mp3;

vendita a buon mercato Scaricare Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors libri iOS

.ISBN

Leave a Reply

Your email address will not be published. Required fields are marked *